Vardenafil

Vardenafil

Product Name: Vardenafil CAS NO.: 224789-15-5 Molecular Formula: C23H32N6O4S Molecular Structure: Appearance: White to almost white crystalline powder, odorless, a little acerbity, soluble in water, ethanol Use: It is pharmaceutical raw material, indicated for the treatment of erectile dysfunction.

Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction that is sold under the trade names Staxyn in India, and Vivanza in Italy.

Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function tosildenafil citrate and tadalafil

The difference between the vardenafil molecule and citrate is anitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group.

Tadalafil is structurally different from both and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.

Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from penetration to ejaculation.

Drug interactions Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure).

Further, Vardenafil causing lengthening of the QT interval. Therefore, it should not be taken by men taking other medications that affect the QT interval (such as amiodarone).

Dose forms Vardenafil is also available under the name Staxyn as a tablet which dissolves on the tongue rather than being swallowed in the form of a pill.

It is available in 2.5 mg, 5 mg, 10 mg, and 20 mg doses in round orange tablets. The normal starting dose is 10 mg Vardenafil should be taken 1 to 2 hours prior to sexual activity, with a maximum dose frequency of once per day. In some territories, such as the UK, only certain doses may be available.