Trilostane 13647-35-3

Product Details Basic Info. Model NO.:CAS: 13647-35-3 Synonym:Vetoryl CAS:13647-35-3 Alias:99% Einecs:237-133-0 Appearance:White Crystalline Powder Molecular Weight:329.4333 Molecular Formula:C20h27no3 Melting Point:264° C Boiling Point:497.8° C at 760 Mmhg Refractive Index:1.61 Export Markets:Global Additional Info.

Packing:According to Every Customers′s Requirements Standard:ISO9001 Origin:Hubei HS Code:1504300090 Production Capacity:5000kg/Month Product Description

Product Description Trilostane Synonym: Vetoryl CAS : 13647-35-3 Alias: 99% Einecs No: 237-133-0 Grade: Pharmaceutical Grade Storage: Shading, confined preservation Appearance: White crystalline powder Molecular Weight: 329.4333 Molecular Formula: C20H27NO3 Melting point: 264° C Boiling point: 497.8° C at 760 mmHg Refractive index: 1.61 Flash point: 254.8° C Vapour Pressur: 5.39E-12mmHg at 25° C Lead time: 1-2 days upon receipt of payment Delivery Term: Products below 200Kg by air; Over 200Kg by ship Delivery Time: Average 6 days by air; 15 days by ship Usage : Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism.

This product also had significantly effect to decreased serum testosterone level. Application: Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. Trilostane blocks an enzyme involved in the production of several steroids including cortisol.

Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.

Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxy steroids dehydrogenase/delta 5,4 keto steroids isomerase, thus blocking synthesis of adrenal steroids.

Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.