Tetracaine HCl

Tetracaine HCl Lidocaine Hydrochloride Tetracaine hydrochloride Lidocaine HCl

Tetracaine HCl Synonyms: Tetracaine hydrochloride; 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester hydrochloride CAS: 136-47-0 EINECS: 205-248-5 Assay: 98.0%-101.0% Standard: USP32 Packing: 1kg/foil bag; 25kg/cardboard drum MF: C15H25ClN2O2 MW: 300.82 Character: Tetracaine hydrochloride (136-47-0) is white crystal or crystalline powder, odorless, slightly bitter taste, a sense of numbness of tongue.

Tetracaine hydrochloride (136-47-0) soluble in water, dissolved in ethanol, insoluble in ether or benzene.. Usage:Tetracaine hydrochloride (CAS NO.136-47-0) is A local anesthetic used topically in opthalmology. Local anesthetic action of Be Proulx Kain strong, 10 times larger than procaine. Toxicity is greater, 10-12 times larger than procaine.

Through the mucosa, mainly used for mucosa anesthesia.

Description:

Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

Applications:

Tetracaine is an Ester Local Anesthetic. The physiologic effect of tetracaine is by means of Local Anesthesia. The chemical classification of tetracaine is Esters.

Anti-paining Anesthetic Anodyne Tetracaine hydrochloride 50-41-9 Procaine 59-46-1 Tetracaine 94-24-6 Pramoxine Hydrochloride 637-58-1 Procaine HCl 1951-5-8 Lidocaine 137-58-6 Dibucaine hydrochloride 1961-12-1 prilocaine 721-50-6 Propitocaine hydrochloride 1786-81-8 Proparacaine hydrochloride 5875-6-9 Linocaine hydrochloride 6108-05-0 Articaine hydrochloride 23964-57-0 Levobupivacaine hydrochloride 27262-48-2 Ropivacaine hydrochloride 132112-35-7 Bupivacaine 2180-92-9 Bupivacaine hydrochloride 14252-80-3