Tenofovir Pharmaceutical Intermediates CAS 147127-20-6

High purity 98% 1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid /Tenofovir Pharmaceutical Intermediates CAS 147127-20-6

Quick detail: CAS :147127-20-6 purity: 98% Molecular Formula:C9H14N5O4P Molecular Weight: 287.21 ATC code:J05AF07 PubChem:CID 464205 DrugBank:DB00300 ChemSpider: 408154  ChEMBL:CHEMBL483  NIAID ChemDB: 080741 Synonyms:1-(6-aminopurin-9-yl)propan-2-yloxymethylphosphonic acid;D,L-TENOFOVIR;TENOFOVIR;(R)-9-(2-PHOSPHONYLMETHOXYPROPYL)-ADENINE;(R)-9-(2-Phosphonomethoxypropyl)Adenine;Tenofovir(ForResearchOnly);(R)-PMPA;[[(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid Molecular Structure

Description: Tenofovir disoproxil fumarate, marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NRTIs), which block reverse transcriptase, a crucial virus enzyme in human immunodeficiency virus 1 (HIV-1) and hepatitis B virus infections.

Application: 1.Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older.[2] This indication is based on analyses of plasma HIV-1 RNA levels and CD4 cell counts in controlled studies of tenofovir in treatment-naive and treatment-experienced adults.

2.Tenofovir is indicated for the treatment of chronic hepatitis B in adults and pediatric patients 12 years of age and older