Ropivacaine Hydrochloride CAS

Product Name: Ropivacaine Hydrochloride

1. Basic Information: Product Name Bupivacaine Hydrochloride Synonym Bupivacaine HCL, Sensorcaine, Marcain, Marcaine, Vivacaine CAS 14252-80-3 MF C18H28N2O.ClH MW 324.89 Assay 99% Quality Standards USP34/Pharma Grade Appearance White powder Package 1kg/Foil bag

Place of Origin China Brand Name SMQ Certification ISO9001, ISO14000, KOSHER MOQ 1kg Ref. Price USD 320/kg Packaging Details 25kg/Drum, 1kg/bag Delivery Time 1-2 days Payment Terms T/T, Western union, Money gram Supply Ability 5000 T/Month

1.Overview: Bupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is commonly marketed under various trade names, including Marcain (Astra Zeneca UK), Marcaine (Carestream Dental, Hospira Inc.), Sensorcaine (Astra Zeneca), and Vivacaine (Septodont).

It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. 2. Medical uses: Bupivacaine is indicated for local infiltration, peripheral nerve block, sympathetic nerve block, and epidural and caudal blocks.

It is sometimes used in combination with epinephrine to prevent systemic absorption and extend the duration of action. The 0.75% (most concentrated) formulation is used in retrobulbar block. It is the most commonly used local anesthetic in epidural anesthesia during labor, as well as in postoperative pain management. 3.

Treatment of overdose: Further information: Lipid rescue Animal evidence indicates intralipid, a commonly available intravenous lipid emulsion, can be effective in treating severe cardiotoxicity secondary to local anaesthetic overdose, and human case reports of successful use in this way. Plans to publicize this treatment more widely have been published. 4.

Mechanism of action: Bupivacaine binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. Without depolarization, no initiation or conduction of a pain signal can occur.