Recombinant human Perforin-1
Specifications
- Origin
- China
- Packaging
- inquiry
- Price Term
- EXW/EX-Work,FOB
- Payment Term
- T/T,L/C,Western Union
Recombinant human Perforin-1 is a Chemical Reagents product. Key specs — Origin: China; Packaging: inquiry; Price Term: EXW/EX-Work,FOB; Payment Term: T/T,L/C,Western Union.
Product Description
Product Name
Recombinant human Perforin-1 Product Type : Recombinant Protein
Code : CSB-EP018668HU
Size : 1mg
Uniprot NO. : P14222
Research Area : Immunology
Protocol
Instructions
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Source : E.coli
Gene Names : PRF1
Expression Region : 22-555aa
Product Info : His-SUMO-tag
Mol. Weight : 75.1kD
Protein Description : Full length
Target details : This protein has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.
