Recombinant Human Junctional adhesion molecule A(F11R)

Product Name: Recombinant Human Junctional adhesion molecule A(F11R) Product Type : Recombinant Protein Code : CSB-YP897579HU >> Yeast CSB-EP897579HU >> E.coli CSB-BP897579HU >> Baculovirus CSB-MP897579HU >> Mammalian cell Size : 1mg Uniprot NO. : Q9Y624 Abbreviation : F11R Storage : Store at -20℃, for extended storage, conserve at -20℃ or -80℃.

Storage Buffer : Tris-based buffer,50% glycerol Species : Homo sapiens (Human) Purity : >90% ( SDS-PAGE ) Sequence : SVT VHSSEPEVRI PENNPVKLSC AYSGFSSPRV EWKFDQGDTT RLVCYNNKIT ASYEDRVTFL PTGITFKSVT REDTGTYTCM VSEEGGNSYG EVKVKLIVLV PPSKPTVNIP SSATIGNRAV LTCSEQDGSP PSEYTWFKDG IVMPTNPKST RAFSNSSYVL NPTTGELVFD PLSASDTGEY SCEARNGYGT PMTSNAVRME AVERNVGV Gene Names : Name:F11R Synonyms:JAM1, JCAM ORF Names:UNQ264/PRO301 Protein Names : Recommended name: Junctional adhesion molecule A Short name= JAM-A Alternative name(s): Junctional adhesion molecule 1 Short name= JAM-1 Platelet F11 receptor Platelet adhesion molecule 1 Short name= PAM-1 CD_antig Expression Region : 28-238 Notes : Repeated freezing and thawing is not recommended.

Store working aliquots at 4℃ for up to one week.

Product Info : His tagged Protein Description : Extracellular domain Target details : Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.

The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor.

Multiple 5 alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.