Recombinant Human Actin-like protein 7B(ACTL7B)

Product Name: Recombinant Human Actin-like protein 7B(ACTL7B) Product Type : Recombinant Protein Code : CSB-YP897577HU >> Yeast CSB-EP897577HU >> E.coli CSB-BP897577HU >> Baculovirus CSB-MP897577HU >> Mammalian cell Size : 1mg Uniprot NO. : Q9Y614 Abbreviation : ACTL7B Storage : Store at -20℃, for extended storage, conserve at -20℃ or -80℃.

Storage Buffer : Tris-based buffer,50% glycerol Species : Homo sapiens (Human) Purity : >90% ( SDS-PAGE ) Gene Names : Name:ACTL7B Protein Names : Recommended name: Actin-like protein 7B Alternative name(s): Actin-like-7-beta Expression Region : 1-415 Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Product Info : His tagged Protein Description : full length protein Target details : This protein is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature.

The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31.

Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known. HGNC : 162