Rat Beta-arrestin-2(ARRB2) ELISA kit

Product Name

Rat Beta-arrestin-2(ARRB2) ELISA kit

Product Type : ELISA Kit

Code : CSB-EL002135RA

Size : 96T,5×96T,10×96T

Uniprot NO. : P29067

Abbreviation : ARRB2

Protein Biological Process 1 : Transport

Alias : ARB2, ARR2, BARR2, DKFZp686L0365, arrestin 3

Species : Rat

Protein Biological Process 3 : Protein transport

Sample Types : serum, plasma, tissue homogenates, cell lysates

Detect Range : 46.88 pg/ml-3000 pg/ml

Sensitivity : 11.72 pg/ml.

Assay Time : 1-5h

Sample Volume : 50-100ul

Detection Wavelengt : 450 nm

Availability : 5-7 working days

Research Area : Signal Transduction

Protocol

Instructions

Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.

Target details : Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.