Pramipexole

Pramipexole

Synonyms: Mirapex, Mirapexin, Sifrol;

CAS Number: 104632-26-0 Molecular Weight: 211.324 g/mol Molecular Formula: C10H17N3S Appearance: white crystalline powder

Specification: Product name: Pramipexole Other Name (S)-4,5,6,7-TETRAHYDRO-N6-PROPYL-2,6-BENZOTHIAZOLEDIAMINE;(s)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole;n'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine;pramipexol;(S)-2-Amino-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazoltetrahydrobenzothiazol;PRAMIPEXOLE: PRAMIPEXOLE DIHYDROCHLORIDE;Pramipexol diclorohidrato monohidrato;PRAMIPEXOLE 2HCL MONOHYDRATE Original China CAS 104632-26-0 Molecular formula C10H17N3S Molecular Weight 211.324 Brand name NJBNSteroid Delivery time within 24 hours upon receipt of payment Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS Purity 99% Package Discreet and Hidden package according to specific requirement Appearance White powder Certification SGS, ISO 9001, KOSHER Payment Terms Western Union, Money Gram , T/T, Bitcoin Minimum Order Quantity 10g Price Negotiable Usage Treating the signs and symptoms of Parkinson disease.

It is also used to treat restless legs MF

Description Pramipexole (Mirapex, Mirapexin, Sifrol) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS). Pramipexole is the generic name for the prescription drug Mirapex, which is used to treat symptoms of Parkinson's disease and restless leg syndrome (RLS).

Mirapex belongs to a class of drugs called dopamine agonists. Scientists believe that it encourages dopamine activity in the body by increasing the sensitivity of dopamine receptors.

In the brain, dopamine acts as a neurotransmitter — helping nerves communicate — which improves movement in restless leg syndrome and helps relax tremors in Parkinson's disease. Originally manufactured by Boehringer Ingelheim under the brand name Mirapex, pramipexole was first approved by the Food and Drug Administration (FDA) in 1997.

Medical Uses

Treating the signs and symptoms of Parkinson disease. It is also used to treat restless legs syndrome (RLS). It may also be used for other conditions as determined by your doctor. Pramipexole is a dopamine agonist. Exactly how pramipexole works is not known. It may increase the action of certain chemical receptors in the brain.

Parkinson's disease is a neurodegenerative disease affecting the substantia nigra, a component of the basal ganglia. The substantia nigra has a high quantity of dopaminergic neurons, which are nerve cells that release the neurotransmitterknown as dopamine.

When dopamine is released, it may activate dopamine receptors in the striatum, which is another component of the basal ganglia. When neurons of the substantia nigra deteriorate in Parkinson's disease, the striatum no longer properly receives dopamine signals.

As a result, the basal ganglia can no longer regulate body movement effectively and motor function becomes impaired.

By acting as an agonist for the D2, D3, and D4 dopamine receptors, pramipexole may directly stimulate the underfunctioning dopamine receptors in the striatum, thereby restoring the dopamine signals needed for proper functioning of the basal ganglia.