Pharmaceutical Raw Material Granisetron Hydrochloride

Product Description

Granisetron Hydrochloride

Granisetron Hydrochloride Brief Description 1. CAS No.: 107007-99-8; MF: C18H24N4O.HCl 2. Grade: Medicine Grade 3. Appearance: White crystalline powder 4. Package: 25kg/Drum 5. Shelf life:  2 Years 6. Competitive price with high quality 7. Conforms to BP/EP/USP 8. Purity: 99%min

Granisetron Hydrochloride Details Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata.

It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.

Granisetron Hydrochloride COA ITEMS SPECIFICATION RESULTS APPEARANCE WHITE TO ALMOST WHITE  CRYSTALLINE POWDER CONFORMS IDENTIFICATION 1). IR COMPLIES TO RS 2). FORWARD REACTION CONFORMS CONFORMS CLARITY AND COLOR OF SOLUTION THE SOLUTION IS CLEAR CONFORMS PH 4.0 TO 6.5 5.5 IMPURITY E  (TCL) IMPURITY A IMPURITY B IMPURITY C IMPURITY D ≤0.5% ≤1.0% ≤0.5% ≤0.2% ≤0.1% 0.07% 0.11% N.D.

0.15% N.D. ANY OTHER IMPURITY ≤0.1% 0.03% TOTAL IMPURITIES ≤1.0% 0.36% LOSS ON DRYING ≤0.5% 0.07% RESIDUE ON IGNITION ≤0.1% 0.06% ASSAY (HPLC) 97.0% TO 102.0% 99.8% CONCLUSION CONFORMS TO EP5

Granisetron Hydrochloride Usage:  Granisetron Hydrochloride is a highly s elective 5-HT 3 receptors inhibitor. It is favourable effective for the prevention and the treatment of nausea and vomiting caused by actinotheraphy, chemotherapy or surgical.

These factor cause intestine chromaffin cell to release of 5-HT which activation 5-HT 3 receptors of nerve centre or vagus and hence resulting from reflection of vomit.

The mechanism of inhibit occur of nausea and vomiting of G ranisetron Hydrochloride is controlled by of 5-HT 3 receptors of antagonistic centre chemistry recept section and peripheral vagus acroteric.   Packaging & Shipping Granisetron Hydrochloride  Packaging: 25kg/bag or according to client request Granisetron Hydrochloride   Delivery Detail:  2 weeks after confirm order.Some of the products can be supplied within 7 days on the strength of EDC warehouse.   Our Services 1. Complex chemical supplier in China with over 5 years of experience.

2. Arrange the orders and shipping with cus requests in time, According to the different countries export policy provide complete customs clearance documents.. 3.

Variety of high quality chemical products with competitive price.   Company Information Hubei Ocean Biotechnology has concentrated on food additives,Vitamins,and some relative chemicals for over 20 years domestic experience and 5 years of international experience.   FAQ 1. What's your payment terms? T/T or L/C. 2. What's your delivery time?

Usually we will arrange the shipment in 7 -15 days,due to different products you choose. 3. How about the packing? Usually we provide the packing as 25 kg / bag or carton,and also as your request bag. 4. How about the validity of the products? According to the products you ordered. 5. What documents you provide?

Usually, we provide Commerical Invoice,  Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know. 6. What is loading port? Usually is Shanghai,Qingdao or Tianjin.