Pharmaceutical Raw Material Ezetimibe

Product Description

Ezetimibe   Brief Description   Molecular Formula:C24H21F2NO3 CAS No.:163222-33-1 Synonyms:1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one Molecular Weight:409.43 Melting Point: 164-166°C Competitive price with high quality Conforms to BP/USP/EP/FCC   Ezetimibe COA ITEM STANDARD RESULTS Appearance White crystalline powder Odorless Conforms Identification IR spectrum HPLC chromatogram Conforms Conforms Solubility Freely soluble in Methanol and Ethanol, Soluble in acetonitrile and isopropanol, Practically insoluble in water Conforms Specific rotation -25°~-29° Conforms Fluorine 8.4%~10.2% 9.5% Related Substance Impurity A ≤0.15% Impurity B ≤0.15% Impurity C ≤0.15% Impurity D ≤0.15% Impurity E ≤0.15% Impurity F ≤0.15% Any other single impurity≤0.10% Total Impurities≤0.80% 0.06% 0.05% 0.03% 0.02% 0.03% 0.02% 0.05% 0.45%\ Residue Solvents Isopropanol≤5000ppm Dichloromethane≤600ppm Methyl tert-butyl ether≤5000ppm Acetic ether≤5000ppm 50ppm 10ppm 15ppm 10ppm Enantiomer ≤0.1% Conforms Water ≤5.0 % 3.0% Residue on ignition ≤0.2% 0.08% Heavy Metals ≤20ppm