Pharmaceutical Raw Material Acycloguanosine / Aciclovir /acyclovir

Product Description

Acycloguanosine / Aciclovir /acyclovir

Brief Description Synonyms:Acycloguanosine; 9-[(2-Hydroxyethoxy)methyl]guanine; 2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one

Molecular Formula:C8H11N5O3

Molecular Weight:225.21

CAS Registry Number:59277-89-3

EINECS:261-685-1

Competitive price with high quality

Conforms to BP/USP/EP/FCC

Aciclovir COA

ITEM SPECIFICATION RESULTS

Appearance A white or almost crystalline powder White crystalline powder

Identification A:IR spectrum

B:HPLC retention time Corresponds to that of reference standard

Corresponds to that of reference standard Complies

Complies

Water Not more than 6.0% 0.3%

Guanine Not more than 0.7% 0.16%

Total other impurities Not more than 1.0% 0.04%

Assay 98.0% to 102.0%,calculated 99.9%

Conclusion Comply with specification with USP 35

Pass test

Medical uses

400 mg pills of aciclovir

Aciclovir is used for the treatment of herpes simplex virus and varicella zoster virus infections, including

Genital herpes simplex (treatment and prevention)

Herpes simplex labialis (cold sores)

Shingles

Acute chickenpox in immunocompromised patients

Herpes simplex encephalitis

Acute mucocutaneous HSV infections in immunocompromised patients

Herpes of the eye and herpes simplex blepharitis (a chronic (long-term) form of herpes eye infection)

Prevention of herpes viruses in immunocompromised people (such as people undergoing cancer chemotherapy)

Oral aciclovir, however, does not appear to decrease the risk of pain after shingles. In those with herpes of the eye, aciclovir was found to be more effective than idoxuridine or vidarabine in relative number of successfully healed eyes.

Intravenous aciclovir is effective to treat severe medical conditions caused by different species of herpes virus family includes severe localized infections of herpes virus, severe genital herpes, chickenpox & encephalitis. It is also effective in systemic or traumatic herpes infections, eczema herpeticum and Herpes simplex meningitis. Reviews of research dating from the 1980s show there is some effect in reducing the number and duration of lesions if aciclovir is applied at an early stage of an outbreak.Recent research shows effectiveness of topical Aciclovir in both the early and late stages of the outbreak as well as improving methodologically and in terms of statistical certainty from previous studies.Aciclovir trials show that this agent has no role in preventing HIV transmission, but it can help slow HIV disease progression in people not taking anti-retroviral therapy (ART). This finding emphasizes the importance of testing simple, inexpensive non-ART strategies, such as aciclovir and cotrimoxazole, in people with HIV.

Pregnancy

Classified as a Category B Drug,the CDC and others have declared that during severe recurrent or first episodes of genital herpes, aciclovir may be used.For severe HSV infections (especially disseminated HSV), IV aciclovir may also be used.Studies in mice, rabbits and rats (with doses more than 10 times the equivalent of that used in humans) given during organogenesis have failed to demonstrate birth defects.Studies in rats in which they were given the equivalent to 63 times the standard steady-state humans concentrations of the drug[Note 1] on day 10 of gestation showed head and tail anomalies.

Aciclovir is recommended by the CDC for treatment of Varicella during pregnancy, especially during the second and third trimesters.

Aciclovir is excreted in the breast milk, therefore it is recommended that caution studies that the nursing infant is exposed to approximately 0.3 mg/kg/day following oral administration of aciclovir to the mother. If nursing mothers have herpetic lesions near or on the breast, breast-feeding should be avoided.

Packaging & Shipping Acycloguanosine Packaging: 25kg/bag or according to client request

Acycloguanosine  Delivery Detail: 1~2 weeks after confirm order.Some of the products can be supplied within 7 days on the strength of EDC warehouse.

Our Services

1. Complex chemical supplier in China with over 5 years of experience.

2. Arrange the orders and shipping with cus requests in time, According to the different countries export policy provide complete customs clearance documents..

3. Variety of high quality chemical products with competitive price.

Company Information

Hubei Ocean Biotechnology has concentrated on food additives,Vitamins,and some relative chemicals for over 20 years domestic experience and 5 years of international experience.

FAQ

1. What's your payment terms?

T/T or L/C.

2. What's your delivery time?

Usually we will arrange the shipment in 7 -15 days,due to different products you choose.

3. How about the packing?

Usually we provide the packing as 25 kg / bag or carton,and also as your request bag.

4. How about the validity of the products?

According to the products you ordered.

5. What documents you provide?

Usually, we provide Commerical Invoice,  Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.

6. What is loading port?

Usually is Shanghai,Qingdao or Tianjin.