Mesterolone

Potent antiestrogen and very Strong Androgen Mesterolone [1 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one] Chemical Structure: 1 alpha-methyl-17 beta-hydroxy-5 alpha-androstan-3-one Effective Dose: 25-50 mg/day Molecular Weight: 304.4716 Molecular Formula: C20H32O2 Melting Point: N/A Release Date: 1960 Effective Dose: 25-200mgs/day Active Life: up to 12 hours Detection Time: 5-6weeks Androgenic: Anabolic Ratio:30-40/100-150 Proviron References: Relative binding affinity of anabolic-androgenic steroids: comparison of the binding to the androgen receptors in skeletal muscle and in prostate, as well as to sex hormone-binding globulin.

Proviron (mesterolone) is basically an orally active DHT (Dihydrotestosterone) preparation. For comparision, we can think of some other orally prepared DHT compounds like Winstrol, Anavar, etc.

Those both act very similarly in mechanism to Proviron, but a more accurate way to think of this compound is as something like "Oral Masteron." As I'm sure you noticed, their anabolic/androgenic ratio is very similar.Remember, DHT is 3 to 4 times as androgenic as testosterone and is, of course, incapable of forming estrogen.

Also, Proviron is quite unique in that a simple look at its 4-ring structure will show us that it is not going to be too liver toxic, since it is not c17-Alpha-Alkylated, as many orals are and this modification (lacking in Proviron) makes drugs more liver toxic. Proviron has a 1-metyhl group added, instead.

Proviron can be an extremely useful help to steroid users in general and to bodybuilders in particular, but one has to know it well as this really is a double edged sword. The active compound in Proviron is called mesterolone, which is in fact a 1-methylated DHT (dihydrotestosterone).

DHT itself is a strongly androgenic compound into which part of testosterone in the body (whether naturally produced or synthetic) is always converted. Proviron doesn't aromatize (and the same is true regarding DHT) but still shows great affinity for aromatase enzyme, thus hindering conversion of other steroids to estrogen.

As such, it can be stacked with aromatizing anabolic steroids. Mesterolone is a very strong androgen, and the most important effects (and side-effects) of this drug are androgenic.