Human Egl nine homolog 1 ELISA kit
Specifications
- Origin
- China
- Packaging
- inquiry
- Price Term
- EXW/EX-Work,FOB
- Payment Term
- T/T,L/C,Western Union
Human Egl nine homolog 1 ELISA kit is a Chemical Reagents product. Key specs — Origin: China; Packaging: inquiry; Price Term: EXW/EX-Work,FOB; Payment Term: T/T,L/C,Western Union.
Product Description
Product Name: Human Egl nine homolog 1 (EGLN1/C1orf12/PNAS-118/PNAS-137) ELISA kit Product Type : ELISA Kit Code : CSB-E17313h Size : 96T,5×96T,10×96T Uniprot NO. : Q9GZT9 Abbreviation : EGLN1 Alias : C1orf12, DKFZp761F179, ECYT3, HIFPH2, HPH2, PHD2, SM20, ZMYND6, HIF prolyl hydroxylase 2|egl nine homolog 1|egl nine-like protein 1|hypoxia-inducible factor prolyl hydroxylase 2|prolyl hydroxylase d Species : Human Sample Types : serum, plasma, tissue homogenates, cell lysates Detect Range : 31.2 pg/ml-2000 pg/ml Sensitivity : 7.8 pg/ml Assay Time : 1-5h Sample Volume : 50-100ul Detection Wavelengt : 450 nm Availability : 3-5 working days Research Area : Others Target details : This protein catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins.
HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex.
Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).