Glucocorticoid

【Effection and purpose】

By the secretion of adrenal cortex in the bundle with a class of steroid hormones, mainly cortisol (cortisol), a regulator of sugar, fat, and protein biosynthesis and metabolism, but also inhibit the immune response, anti-inflammatory, anti- drug, anti-shock effect.

【Physiological role】

1, to promote gluconeogenesis and glycogen synthesis, inhibition of aerobic glucose oxidation and anaerobic glycolysis, leaving the increase in blood sugar origin, path reduction, increased blood sugar.

2 and improve the proteolytic enzyme activity, reduced protein synthesis, and promote a variety of tissues (lymph node, muscle, skin, bone, connective tissue, etc.) in the protein degradation, and promote lipolysis, inhibiting its synthesis, to achieve weight loss weight-loss results.

【Pharmacological effects】

1, in the early stage of inflammation, inhibition of telangiectasia, reduce leakage and edema, but also inhibited the infiltration of white blood cells and phagocytosis, and reduce inflammation symptoms. In the late inflammation, inhibit capillary and fibroblast proliferation, delaying the formation of granulation tissue. Are valid for all kinds of inflammation.

2, induced the synthesis of anti-inflammatory factor to reduce the systemic inflammatory response and tissue damage, anti-shock effect.

nbsp; 3, the induction of inflammatory protein synthesis. Leukocyte protease inhibition of the generation of inflammation.

4 induced apoptosis of inflammatory cells.

5, serious infections, such as septicemia, meningitis, fever and improvement of symptoms with good effect.

6, for the acute and chronic insufficiency of adrenal cortex function, anterior pituitary and adrenal gland dysfunction after subtotal of complementary and alternative therapies.

7, severe acute infection or inflammation, severe acute bacterial infections in the application of adequate and effective antimicrobial agents at the same time. Compatibility GCS, use of its anti-inflammatory, anti-drug role, can relieve symptoms, help patients Through the crisis.

8, for psoriasis, eczema, contact dermatitis, can be topical, but pemphigus and exfoliative dermatitis, skin diseases and other serious systemic administration is required.

9, malignant lymphoma, advanced breast cancer, prostate cancer treatment are effective.