Ethisterone CAS NO.: 434-03-7

English Synonyms: 4,17ALPHA-PREGNEN-17BETA-OL-20-YN-3-ONE;4,17a-pregnen-17b-ol-20-yn-3-one;4,17A-PREGNEN-17B-OL-20-YNE;4-ANDROSTEN-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE;(8R,9S,10R,13S,14S,17R)-17-ETHYNYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE;ANHYDROHYDROXYPROGESTERONE;ANHYDROXYPROGESTERONE;17BETA-HYDROXY-4,17ALPHA-PREGNEN-20-YN-3-ONE

CAS NO.: 434-03-7

Assay: 98%

Molecular Formula:C21H28O2

Molecular Weight:312.45

Packing:1kg / foil bags

Appearance: White or milky white crystalline powder.

Melting point 269-275 ℃, at 190-195 ℃ in high vacuum sublimation. Slightly soluble in ethanol, acetone, chloroform and vegetable oils, in fact, insoluble in water

Usage:Similar to the yellow like progesterone, for the treatment of excessive menstrual bleeding, or sub-camps can also be used to prevent threatened abortion and habitual abortion. Progesterone is a progestin by the corpus luteum and the placenta secreted is more than the synthetic

Product description

Ethisterone (pregneninolone, 17α -ethynyltestosterone or 19-norandrostane) is a progestin. It is the 17α -ethynyl analog of testosterone, and was synthesized in 1938 by Hans Herloff Inhoffen, Willy Logemann, Walter Hohlweg, and Arthur Serini at Schering AG in Berlin and marketed in Germany in 1939 as Proluton C and by Schering in the U. S. In 1945 as Pranone. It was the first orally-active progestin.

Ethisterone was also marketed in the U. S. From the 1950s into the 1960s under a variety of trade names by other pharmaceutical companies that had been members of the pre-World War II European hormone cartel (Ciba, Organon, Roussel).

Dosage The treatment of dysfunctional uterine bleeding: Take 1 2.5mg every 8 hours, (in case of emergency medicine 1 times every 3 hours, until the bleeding decreased obviously changed after 8 hours 1 times), and then gradually reduced, until the maintenance dose of 2.5mg 1 times daily, and even last 20 days; Also can be in the bleeding stops, daily add oral ethinyl estradiol 0.05mg or diethylstilbestrol 1mg, total 20 days.

Infertility: Oral Ethisterone 2.5mg and ethinylestradiol 0.05mg, 1 times a day, and even last 20 days, total of 3 cycles.

Dysmenorrhea, endometriosis: Begin 5-7 days after menstruation, orally 1 times daily 2.5mg, and even last 20 days.

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