Estriol CAS: 50-27-1

Synonyms: oestriol; 1,3,5(10)-Estratriene-3,16a,17b-triol

CAS: 50-27-1

EINECS: 200-022-2

Assay: 97.0%-102.0%, USP30.

Packing: foil bag or tin.

Delivery: Express courier.

Character: White crystalline powder.

Usage: A metabolite of Estradiol. An estrogenic metabolite considerably less potent than the hormone Estradiol. pharmaceutical material, Steroid hormone, estrogen.

Standards:USP27

description

Estriol's strength is actually found in its weakness. Tests show that while relieving the symptoms of perimenopause and menopause, estriol doesn't seem to increase the risk of breast cancer. This is because estriol binds to the estrogen receptors on the breast cells, but it has much weaker activity. Therefore, it actually blocks the stronger estradiol from binding to those cells and subjecting them to the higher estrogenic activity which has been shown to be protective against breast cancer. And for women who have difficulty tolerating stronger estrogens for the treatment of hormonal imbalance due to aging, estriol is often the right choice.

Application

Hormonal contraception

A chemical derivative of estradiol, ethinyl estradiol with maximum dosage 200 µg, is a major component of hormonal contraceptive devices. Combined forms of hormonal contraception contain ethinyl estradiol and a progestin, which both contribute to the inhibition of GnRH, LH, and FSH, which accounts for the ability of these birth control methods to prevent ovulation and thus prevent pregnancy. Other types of hormonal birth control contain only progestins and no ethinyl estradiol.

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