Cetirizine hydrochloride

Cetirizine hydrochloride

Synonyms: (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)aceticaciddihydro;(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-aceticacidihyd;ucb-p071;ZYRTEC;2-(2-{4-[(4-chlorophenyl)(phenyl)-methyl]piperazino}ethoxy)acetic acid dihydrochloride;AKOS 92015;CETIRIZIN DIHYDROCHLORIDE;CETIRIZINE 2HCL CAS: 83881-52-1 MF: C21H26Cl2N2O3 MW: 425.35

Chemical Properties Crystalline Solid Usage respiratory stimulant Usage A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.

Usage long acting calcium channel blocker Biological Activity Histamine H 1 receptor antagonist that displays selectivity over other receptors at concentrations up to 10 μ M. A non-sedating antihistamine that inhibits histamine release and eosinophil chemotaxis during secondary phase allergic response.

Inhibits activation of eosinophils, neutrophils and monocytes in vivo .