Capsaicin

Capsaicin

Synonyms: (E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE;(E)-CAPSAICIN;(E)-N-([4-HYDROXY-3-METHOXYPHENYL]METHYL)8-METHYL-6-NONEAMIDE;(E)-N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE;CAPSAICIN;CAPSAICINE;CAPSAICIN, NATURAL;FEMA 3404 CAS: 404-86-4 MF: C18H27NO3 MW: 305.41 EINECS: 206-969-8

Chemical Properties Off-White Crystalline Solid Usage A representative lot is a 5:1 E:Z mixture. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic. Usage K channel blocker; multiple sclerosis therapy Usage analgesic (topical), depletes Substance P, neurotoxic Usage Capsaicin analogue (C175680).

It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic. Biological Activity Prototypic vanilloid receptor agonist (pEC 50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a subset of primary afferent sensory neurons, with subsequent antinociceptive and anti-inflammatory effects.

Reversibly inhibits aggregation of platelets. Also available as part of the Vanilloid TRPV1 Receptor Tocrisetâ„¢ .