Anastrozole

Anastrozole Product Name:Anastrozole Another Name:10-Methoxy-5H-dibenz[b,f]azepine-5-carbonylchloride;1,3-Benzenediacetonitrile,a,a,a',a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)- (9CI);2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]di(2-methylpropionitrile);2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile;Asiolex;Anastrol; CAS:120511-73-1 Molecular Weight:293.37 Molecular Formula:C17H19N5 Molecular Weight 293.37 CAS Registry Number 120511-73-1 Properties anastrozole Melting point 81-82 oC Name:Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile Product name: Anastrozole Synonym: Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile Assay99% Molecular formula: C17H19N5 Molecular weight: 293.37 Appearance: white crystal powder Medicinal categories: non-steroidal aromatase inhibitors Indication: Anastrozole is used for Postmenopausal women with advanced breast cancer that tamoxifen and other anti-estrogen therapy can not control.

For the estrogen receptor-negative patients, can think about the anastrozole if the tamoxifen showed positive clinical response Pharmacology: Anastrozole as a potent, selective nonsteroidal aromatase inhibitors, it can inhibit the postmenopausal patients with adrenal suppression generated androstenedione intoestrone, significantly reduce plasma estrogen levels.

And inhibiting of breast tumor growth. Anastrozole significantly affect on adrenal corticosteroids or aldosterone.