1-Methyl-2-pyrrolidinone

1-Methyl-2-pyrrolidinone Synonyms: M-PYROL(R);N-METHYLPYROLIDONE;N-METHYLPYRROLID-2-ONE;N-METHYLPYRROLIDINONE;N-METHYLPYRROLIDNONE;N-METHYLPYRROLIDONE;NMP-T;NMP-EL

CAS: 872-50-4

MF: C5H9NO

MW: 99.13

EINECS: 212-828-1

Chemical Properties colourless or light yellow liquid with an amine odour

Usage high purity grade for ICP-MS detection

Usage It is a versatile industrial solvent. NMP is currently approved for use only in veterinary pharmaceuticals. The determination of the disposition and metabolism of NMP in the rat will contribute toward understanding the toxicology of this exogenous chemical which man may likely be exposed to in increasing amounts.

General Description A clear colorless liquid with a "fishlike" odor. Denser than water. Flash point 199°F. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion.

Air & Water Reactions Soluble in water.

Reactivity Profile This amine is a very mild chemical base. 1-Methyl-2-pyrrolidinone does tend to neutralize acids to form salts plus water. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard Inhalation of hot vapors can irritate nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes causes irritation. Repeated and prolonged skin contact produces a mild, transient irritation.

Fire Hazard Special Hazards of Combustion Products: Toxic oxides of nitrogen may be formed in fire.