10-Deacetylbaccatin III
Specifications
- Origin
- the Pacific yew tree (Taxus brevifolia) etc.
- Packaging
- 1kg/foil bag
- Price Term
- EXW/EX-Work,FOB
- Payment Term
- T/T,L/C,Western Union
10-Deacetylbaccatin III is a Eye Health Supplies product. Key specs — Origin: the Pacific yew tree (Taxus brevifolia) etc.; Packaging: 1kg/foil bag; Price Term: EXW/EX-Work,FOB; Payment Term: T/T,L/C,Western Union.
Product Description
10-Deacetylbaccatin III
Name: 10-Deacetylbaccatin III Synonym: 10-DAB III; 10-Deacetyl Baccatin III CAS: 32981-86-5 EINECS: 418-680-6 Assay: NTL98% M.F: C29H36O10 M.W: 544.59 Specific Rotate: -44.5° (c=1, methanol 25 °C) MP: 231-236 °C BP: 716.8 oC at 760 mmHg Density: 1.41 g/cm3 Appearance: white solid Application: Used as a chemical intermediate in the preparation of the anti-cancer drug paclitaxel (Taxol).
Package: 1kg/foil bag MOQ: 100g Price: 25.5USD/G Jump to: navigation, search 10-Deacetylbaccatin III Names IUPAC name (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca(3,4)benz(1,2-b)oxet-5-one Other names 10-Deacetylbaccatin III 10-Deacetylbaccatine III Identifiers CAS Number 32981-86-5 N ChEBI CHEBI:18193 Y ChEMBL ChEMBL393912 Y ChemSpider 135935 Y Jmol 3D model Interactive image PubChem 154272 InChI InChI=1S/C29H36O10/c1-14-17(31)12-29(36)24(38-25(35)16-9-7-6-8-10-16)22-27(5,23(34)21(33)20(14)26(29,3)4)18(32)11-19-28(22,13-37-19)39-15(2)30/h6-10,17-19,21-22,24,31-33,36H,11-13H2,1-5H3/t17-,18-,19+,21+,22-,24-,27+,28-,29+/m0/s1 Y Key: YWLXLRUDGLRYDR-ZHPRIASZSA-N Y SMILES CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O Properties Chemical formula C29H36O10 Molar mass 544.59 g/mol Appearance colorless solid Melting point 234 °C (453 °F; 507 K) Solubility in water insoluble Solubility soluble in methanol Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?) Infobox references
10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species. 10-Deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere).
10-deacetylbaccatin III 10-O-acetyltransferase converts 10-deacetylbaccatin to baccatin III:
acetyl-CoA + 10-deacetylbaccatin III CoA + baccatin III
