Green Coffee Bean Extract （vanessa@nutra-max.com） - vanessa@nutra-max.com

Green Coffee Bean Extract Chlorogenic Acid（vanessa@nutra-max.com）绿咖啡豆提取物
Product Item: OHI00000253
Latin Name: Chlorogenic Acid
CAS No.: 327-97-9
Active Ingredient: Chlorogenic Acid
Specifications: 50%|98%|99%
Test Method: HPLC
Green Coffee Bean Extract
Green Coffee Bean Extract is sourced from Europe and is standardized to more than 99% Chlorogenic Acid. Chlorogenic Acid is the compound present in coffee.
Which has been long known as for its beneficial properties. This active ingredient akes Green Coffee Bean an excellent agent to absorb free oxygen radicals; as well as helping to avert hydroxyl radicals, both which contribute to degradation of cells in the body.


Green Coffee Beans have strong polyphenols which act to help reduce free oxygen radicals in the body, but it is standardized to more than 99% Cholorgenic Acid, a dietary polyphenol that helps to regulate metabolism.

Test results showed Green Coffee Bean had more than double the rate of oxygen radical absorbance capability when compared to green tea and grape seed extracts.

Green Coffee Bean Extract is made from the green beans of the Coffea Arabica plant. There are two types of coffee plants, arabica and robusta. The arabica is higher in quality and higher in chlorogenic and caffeic acids, two primary compounds responsible for anti-oxidant activity.

This extract contains at least 99% Chlorogenic Acid, a dietary polyphenol. Along with being a great anti-oxidant, there is evidence that Chlorogenic Acid may have biological effects in the small intestine that alter patterns of glucose uptake, helping to regulate the metabolism.

The Caffeic Acids act as stimulant, providing a safe energy boost while being naturally low in caffeine. Boiled coffee drinks contain cafestol which is associated with the negative effects of using coffee as a stimulant, this is not present in green coffee beans or the extract.

Green Coffee Bean is also great for sports formulations because it can work to stimulate the production of cortisone and adrenalin in the body resulting in increased stamina.

HEALTH BENEFITS
Works in two ways as a powerful anti-oxidant reducing free oxygen radicals
Helps to regulate the body's metabolism by inhibiting glucose 6 phosphate
Increases Stamina by stimulating the production of cortisone and adrenalin
Can increase the effectiveness of pain killers, especially for migraine medications
Can help to reduce the risk of diabetes, studies report 30% in women and over 50% in men
Helps the body burn a higher proportion of lipids to carbohydrates, which can help avoid muscle fatigue

More about Chlorogenic Acid:
Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major phenolic compound in coffee, but is also found widespread in plants and can be isolated from the leaves and fruit This compound, long known as an antioxidant, also slows the release of glucose into the bloodstream after a meal.

Biological importance
This acid is an important factor in plant metabolism. It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters; at concentrations as high as 100 µg/L, does not inhibit the 5-lipoxygenase activity of ionophore-stimulated human polymorphonuclear leukocytes.

Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to the prevention of Type 2 Diabetes Mellitus and cardiovascular disease .

Chlorogenic acid is an important factor in plant metabolism. It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters.Chlorogenic acid, at concentrations as high as 100 um, does not inhibit the 5-lipoxygenase activity of ionophore-stimulated human polymorphonuclear leukocytes.

Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major phenolic compound in coffee; daily intake in coffee drinkers is 0.5–1 g. Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to the prevention of cardiovascular disease.

Chlorogenic acid has been proven in animal studies in vitro to inhibit the hydrolysis of the glucose-6-phosphate enzyme in an irreversible fashion. This mechanism allows chlorogenic acid to reduce hepatic glycogenolysis (transformation of glycogen into glucose) and to reduce the absorption of new glucose. In addition, in vivo studies on animal subjects have demonstrated that the administration of chlorogenic acid lessens the hyperglycemic peak resulting from the glycogenolysis brought about by the administering of glucagen, a hyperglycemiant hormone. The studies also confirmed a reduction in blood glucose levels and an increase in the intrahepatic concentrations of glucose-6-phosphate and of glycogen.

Chlorogenic acid can be used as anti-infectious active ingredient, it has wide anti-virus, anti-bacteria effects, and has relatively lower toxicity and side-effects. It has obvious anti-infectious effects, and does not like to lead Anti-microbial Resistance.

Due to its obvious anti-infectious effects, it not only can be used in pharmaceutical field but can be used widely in many other fields like food, feed additives, cosmetics also.

Chlorogenic Acid—Best ingredients for cosmetic products
I. Strong Anti-oxidant ability
II. 100% water soluble
III. Very stable at normal temperature
IV. Pure white
V. No hypersusceptibility
VI. 100% natural
VII. 100% safe for green caffee bean is drink as a tea for more than 2000 years in worldwide.
Basic Information of Chlorogenic Acid
Molecular formula: C16H18O9
Molecular weight: 354.31
CAS No.: 327-97-9
Melting point:205-209°C
Solubility: Good solubility in water
Appearance: Fine crystal powder
Color: White
Specific Rotation [α]: -36° (c=1, H2O)
Molecular structure:


What is Chlorogenic acid:
Chlorogenic acid is a phenolic natural product isolated from the leaves and fruits of dicotyledonous plants, including the coffee bean, . Structurally, chlorogenic acid is the ester of caffeic acid with the 3-hydroxyl group of quinic acid.

Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major phenolic compound in coffee, but is also found widespread in plants and can be isolated from the leaves and fruit . This compound, long known as an antioxidant, also slows the release of glucose into the bloodstream after a meal.

Biological importance
This acid is an important factor in plant metabolism. It is also an antioxidant and an inhibitor of the tumor promoting activity of phorbol esters; at concentrations as high as 100 µg/L, does not inhibit the 5-lipoxygenase activity of ionophore-stimulated human polymorphonuclear leukocytes.

Chlorogenic acid and caffeic acid are antioxidants in vitro and might therefore contribute to the prevention of Type 2 Diabetes Mellitus and cardiovascular disease .

HPLC Chromatogram of 99% Chlorogenic Acid


Why Organic Herb Inc. Chlorogenic acid:
1.Organic Herb Inc. Chlorogenic acid is 100% extracted from natural plant, very safe and more bioactive.
2.Organic Herb Inc. have the most purity Chlorogenic acid, Our Chlorogenic acid is a 99% purity product tested by HPLC and just one peak on HPLC chromatogram. Impurity almost can’t be detected. Our Chlorogenic acid has passed the tests of more than 10 USA independent labs.
3.Organic Herb Inc. Chlorogenic acid almost have no unpleasant taste compare to other Chlorogenic acid and it can be easier to take by oral.
4.Organic Herb Inc. offer Chlorogenic acid at a very lower price with a very high and uniform quality.
5.More important --- we have a very large output to meet our customers'big and continual orders