Atorvastatin calcium - CAS No. 134523-03-8

Atorvastatin calcium - CAS No. 134523-03-8
:
Atomax Chemicals Co.,Ltd
: 2013-09-25 23:21:24
:
Atorvastatin calcium

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Description Of Atorvastatin calcium - CAS No. 134523-03-8

Atorvastatin calcium - CAS No. 134523-03-8 Specificaton & Trade Terms

ModelCAS No. 134523-03-8
Place Of Originchina
Price TermEX-Work
Payment TermT/T
【Appearance】
White Crystalline Powder
【Melting Point】176-178°C
【Flash Point】390.6 °C
【Water】Slightly soluble
【Usage】
A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia

【Biological Activity】
Potent HMG-CoA reductase inhibitor (IC 50 = 8 nM). Reduces circulating LDL-C by inhibiting cholesterol biosynthesis and inducing expression of LDL receptors. Inhibits smooth muscle cell proliferation in vitro and exhibits antinociceptive effects in the inflammatory hypernociception model.
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